产品货号：
Z21086
中文名称：
Mouse RING1抗体
英文名称：
Anti-Mouse RING1 Antibody (C-term)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Mouse RING1 Antibody (C-term) |
| 指标别名 | E3 ubiquitin-protein ligase RING1;632-;Polycomb complex protein RING1;RING finger protein 1;Transcription repressor Ring1A;Ring1;Ring1A;Rnf1 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse |
| 应用范围 | WB |
| 基因名称 | Ring1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This Mouse Ring1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 306-340 amino acids from the C-terminal region of human Mouse Ring1. |
| 计算分子量 | 43kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A,thereby playing a central role in histone code and gene regulation.H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex,a complex class required to maintain the transcriptionally repressive state of many genes,including Hox genes,throughout development.PcG PRC1 complex acts via chromatin remodeling and modification of histones,rendering chromatin heritably changed in its expressibility.Compared to RNF2/RING2,it does not have the main E3 ubiquitin ligase activity on histone H2A,and it may rather act as a modulator of RNF2/RING2 activity (By similarity). |
| Uniprot ID | O35730 |
相关搜索：Mouse RING1抗体，Mouse RING1(C-term)多抗，Anti-Mouse RING1 Antibody (C-term)